Dissolution Enhancement of Artemisinin with .BETA.-Cyclodextrin
نویسندگان
چکیده
منابع مشابه
Aripiprazole-Cyclodextrin Binary Systems for Dissolution Enhancement: Effect of Preparation Technique, Cyclodextrin Type and Molar Ratio
Objective(s): The aim of this work was to investigate the effect of the natural and the chemically modified form of cyclodextrins namely; β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) respectively on the solubility and dissolution rate of aripiprazole; an antipsychotic medication showing poor aqueous solubility. Materials and Methods: Phase solubility of ar...
متن کاملaripiprazole-cyclodextrin binary systems for dissolution enhancement: effect of preparation technique, cyclodextrin type and molar ratio
objective(s): the aim of this work was to investigate the effect of the natural and the chemically modified form of cyclodextrins namely; β-cyclodextrin (β-cd) and hydroxypropyl-β-cyclodextrin (hp-β-cd) respectively on the solubility and dissolution rate of aripiprazole; an antipsychotic medication showing poor aqueous solubility. materials and methods: phase solubility of aripiprazole with t...
متن کاملAripiprazole-Cyclodextrin Binary Systems for Dissolution Enhancement: Effect of Preparation Technique, Cyclodextrin Type and Molar Ratio
OBJECTIVE(S) The aim of this work was to investigate the effect of the natural and the chemically modified form of cyclodextrins namely; β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) respectively on the solubility and dissolution rate of aripiprazole; an antipsychotic medication showing poor aqueous solubility. MATERIALS AND METHODS Phase solubility of aripiprazole with the...
متن کاملPhysicochemical Characterization and Dissolution Enhancement of Loratadine–Hydroxypropyl-β-cyclodextrin Binary Systems
Loratadine, a Class II drug is a second generation antihistaminic agent, which is poorly water soluble with low bioavailability. Loratadine is practically insoluble in water and as such it exhibits poor variable oral bioavailability. Loratadine needs enhancement of solubility and dissolution rate to improve its oral bioavailability and therapeutic efficacy. In the present investigation, studies...
متن کاملPhysicochemical characterization and in vitro dissolution behaviour of celecoxib-beta-cyclodextrin inclusion complexes.
In this study, attempts were made to investigate the effects of beta-cyclodextrin (beta-CD) on the aqueous solubility and dissolution rate of celecoxib. Inclusion complexes were prepared by the kneading method and characterized by SEM, NMR, IR, DSC, and X-ray powder diffraction. Dissolution rate of the complexes was significantly greater than that of the corresponding physical mixtures and pure...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2011
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.59.646